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Background Type 2 diabetes mellitus (T2DM) has become a chronic disease serious harm to human health Complications of the blood pipe are the main cause of disability and death in diabetic patients including vascular lesions that directly affects the prognosis of patients with diabetes and survival.
Muscle atrophy in patients with Type 2 Diabetes Mellitus
Basic pathogenic differences exist in the two forms of diabetes mellitus T1DM is immune mediated and T2DM is mediated by metabolic mechanisms These mechanisms differentially affect early βcell dysfunction and eventual fate Over the past decade major advances have been made in the field mostly delivered by studies on βcells in human disease.
KEGG DISEASE: Type 2 diabetes mellitus
The PI3K/AKT pathway in obesity and type 2 diabetes Obesity and type 2 diabetes mellitus are complicated metabolic diseases that affect multiple organs and are characterized by hyperglycaemia Currently stable and effective treatments for obesity and type 2 diabetes mellitus are not available.
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PDF fileCon sidering the elevated systemic inflammation and activation of the NFκB pathway in T2DM skeletal muscle (40 125) the NFκB pathways are a promising but relatively unexplored area of T2DM mediated muscle atrophy 98 • Diabetes inflammation and atrophy in.